Illuminating the landscape of host-pathogen interactions with the bacterium Listeria monocytogenes.
نویسنده
چکیده
Listeria monocytogenes has, in 25 y, become a model in infection biology. Through the analysis of both its saprophytic life and infectious process, new concepts in microbiology, cell biology, and pathogenesis have been discovered. This review will update our knowledge on this intracellular pathogen and highlight the most recent breakthroughs. Promising areas of investigation such as the increasingly recognized relevance for the infectious process, of RNA-mediated regulations in the bacterium, and the role of bacterially controlled posttranslational and epigenetic modifications in the host will also be discussed.
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 108 49 شماره
صفحات -
تاریخ انتشار 2011